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Invitrogen
Chlorpromazine Recombinant Mouse Monoclonal Antibody (4F6)
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Chlorpromazine Antibody (MA566579) in SDS-PAGE
SDS-PAGE characterization of Chlorpromazine under reducing conditions. Lane M: Protein marker (kDa); Lane CPZ: Purified Chlorpromazine Recombinant Monoclonal (Product # MA566579). Chlorpromazine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-622.
产品信息
MA566579
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4F6
抗原
Conjugate of CPZ hapten and KLH.
偶联物
形式
Liquid
浓度
11 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Chlorpromazine, developed in the early 1950s, is a phenothiazine antipsychotic primarily used to treat schizophrenia and other psychiatric disorders. It functions by blocking dopamine receptors in the brain, which helps alleviate symptoms of psychosis. Chlorpromazine is located on chromosome 22q13.1, and its structure includes a tricyclic phenothiazine core with a side chain that influences its pharmacological activity. The drug has been repurposed for various treatments, including anti-leukaemic therapy and triple-negative breast cancer, due to its ability to cross the blood-brain barrier and interact with central nervous system pathways. Chlorpromazine's versatility extends to its use in novel drug delivery systems, such as the drug-in-cyclodextrin-in-liposome platform, enhancing its therapeutic potential.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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