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Invitrogen
Ciprofloxacin Recombinant Mouse Monoclonal Antibody (4D7)
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Ciprofloxacin Antibody (MA566574) in SDS-PAGE
SDS-PAGE characterization of Ciprofloxacin under reducing conditions. Lane M: Protein marker (kDa); Lane CIP: Purified Ciprofloxacin Recombinant Monoclonal (Product # MA566574). Ciprofloxacin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-424.
产品信息
MA566574
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4D7
抗原
Conjugate of CIP hapten and KLH.
偶联物
形式
Liquid
浓度
6.3 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Ciprofloxacin is a fluoroquinolone antibiotic that is widely used to treat bacterial infections. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and repair. Structurally, ciprofloxacin is characterized by a quinolone core with a fluorine atom at the 6-position, enhancing its antibacterial activity. The development of ciprofloxacin derivatives and hybrids, such as ciprofloxacin-sulfonamide hybrids, aims to improve its efficacy and reduce side effects, particularly central nervous system-related ones. These derivatives are synthesized through acylation processes involving various linkers, such as acetamide and propanamide, to enhance absorption and activity. Despite its potency, the emergence of drug-resistant pathogens necessitates ongoing research to develop novel ciprofloxacin-based antibacterials. The gene location and specific biosimilar pathways are not detailed in the current literature, focusing instead on synthetic strategies and biological effects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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