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Progen
Clathrin Monoclonal Antibody (CHC5.9)
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产品信息
61017PROGEN
产品规格
种属反应
Amphibian,
Bovine,
Human,
Pig,
Rat
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
CHC5.9
抗原
Coated Vesicles (Clathrin) Of Bovine Brain
偶联物
形式
Lyophilized
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute lyophilized product with 1 mL distilled water.
CHC5.9 represents an excellent marker for detection of receptor mediated endocytosis.Reactive polypeptide: MW 180 000 polypeptide (clathrin heavy chain) from coated vesicles of various tissues.Structures and tissues specifically detected: Coated vesicles of different organs and tissues (eg brain, mammary gland, ovaries).Reactivity on cultured cell lines: HeLa, SV-40, RVF-SMC.
靶标信息
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain on chromosome 17; Clathrin heavy chain on chromosome 22; clathrin, heavy chain (Hc); clathrin, heavy chain-like 1; clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH-17; CLH-22
基因别名: CHC; CHC17; CHC22; CLH-17; CLH17; CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034
UniProt ID: (Human) Q00610, (Bovine) P49951, (Human) P53675, (Rat) P11442
Entrez Gene ID: (Human) 1213, (Pig) 100271929, (Bovine) 281080, (Human) 8218, (Rat) 54241
double-stranded RNA binding
structural molecule activity
protein binding
protein kinase binding
clathrin light chain binding
poly(A) RNA binding
protein domain specific binding
identical protein binding
disordered domain specific binding
arrestin family protein binding
signal transducer activity
protein C-terminus binding
ankyrin binding
heat shock protein binding
peptide binding
vesicle coat protein
osteoblast differentiation
intracellular protein transport
receptor-mediated endocytosis
mitotic nuclear division
antigen processing and presentation of exogenous peptide antigen via MHC class II
receptor internalization
transferrin transport
retrograde transport, endosome to Golgi
Wnt signaling pathway, planar cell polarity pathway
negative regulation of hyaluronan biosynthetic process
negative regulation of protein localization to plasma membrane
autophagy
clathrin coat assembly
cell division
signal transduction
anatomical structure morphogenesis
positive regulation of glucose import
Golgi organization
vesicle-mediated transport
