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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Claudin-22
基因别名: 2210404A22Rik; 5330431C14Rik; 9530051B05Rik; CLDN21; CLDN22
UniProt ID: (Human) Q8N7P3, (Mouse) Q9D7U6
Entrez Gene ID: (Human) 53842, (Mouse) 75677