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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:3,000 | - |
免疫细胞化学 (ICC/IF) |
1:100-1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fragment corresponding to a region within amino acids 1 and 166 of Cofilin 2 (muscle) (Uniprot ID#Q9Y281) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.28 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7, with 20% glycerol, 1% BSA |
内含物 |
0.025% ProClin 300 |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11156612 |
Recommended positive controls: H1299, HCT116, Mouse brain, rat heart.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (89%), Xenopus laevis (87%), Pig (100%), Chicken (96%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COF2; cofilin 2 (muscle); Cofilin, muscle isoform; Cofilin-2; HGNC:1875; nemaline myopathy type 7
基因别名: CFL2; NEM7
UniProt ID: (Human) Q9Y281, (Mouse) P45591
Entrez Gene ID: (Human) 1073, (Rat) 366624, (Mouse) 12632
分子生物学功能:
non-motor actin binding protein
