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Invitrogen
Collagen II Polyclonal Antibody
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产品信息
PA1-86055
产品规格
种属反应
Bovine
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Bovine type II collagen
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Affinity chromatography
保存液
BBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-1 type II collagen; CGA; Collagen 2; Collagen alpha-1(II) chain; collagen, type II, alpha 1; MGC131516; pro-alpha 1(II); unnamed protein product
基因别名: CB11; COL2A1
UniProt ID: (Bovine) P02459
Entrez Gene ID: (Bovine) 407142
cartilage condensation
tissue homeostasis
endochondral ossification
chondrocyte differentiation
heart morphogenesis
proteoglycan metabolic process
central nervous system development
visual perception
sensory perception of sound
regulation of gene expression
inner ear morphogenesis
palate development
limb bud formation
embryonic skeletal joint morphogenesis
cartilage development involved in endochondral bone morphogenesis
otic vesicle development
cellular response to BMP stimulus
anterior head development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
