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产品信息
MA5-35021
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
CL4540
抗原
Synthetic Peptide corresponding to Human Connexin 30
偶联物
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2848926
产品详细信息
Immunogen sequence: RSKRAQTQKN HPNHALKESK
靶标信息
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: connexin 30; Connexin-30; Cx30; ectodermal dysplasia 2, hidrotic (Clouston syndrome); Gap junction beta-6 protein; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa
基因别名: CX30; DFNA3; DFNA3B; DFNB1B; ECTD2; ED2; EDH; GJB6; HED; HED2
UniProt ID: (Human) O95452
Entrez Gene ID: (Human) 10804
分子生物学功能:
gap junction
