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产品信息
701297
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
20H24L10
抗原
Peptide corresponding to amino acids 126-164 of human copeptin
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2532465
产品详细信息
This antibody is predicted to react with bovine, canine, chimpanzee, non-human primate, rabbit, ovine and porcine based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Copeptin is a member of vasopressin/oxytocin family. It is a 39-amino acid peptide produced from cleavage of preprovasopressin during precursor processing, and is released along with the hormone arginine vasopressin. Copeptin acts to ensure the proper structural formation of arginine vasopressin during precursor processing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antidiuretic hormone; AVP-NPII; copeptin; neurohypophyseal; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin
基因别名: ADH; ARVP; AVP; AVP-NPII; AVRP; VP
UniProt ID: (Human) P01185
Entrez Gene ID: (Human) 551
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
renal water homeostasis
generation of precursor metabolites and energy
water transport
apoptotic process
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of female receptivity
grooming behavior
locomotory behavior
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of cell growth
positive regulation of cAMP biosynthetic process
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
positive regulation of peptidyl-serine phosphorylation
response to testosterone
response to nicotine
social behavior
regulation of renal sodium excretion
vasoconstriction
hyperosmotic salinity response
maternal behavior
negative regulation of apoptotic process
penile erection
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
sodium-independent organic anion transport
response to ethanol
positive regulation of vasoconstriction
negative regulation of transmission of nerve impulse
ERK1 and ERK2 cascade
protein kinase C signaling
negative regulation of release of cytochrome c from mitochondria
