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Invitrogen
Crk Polyclonal Antibody
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产品信息
PA5-17649
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues surrounding Trp169 of human CrkII protein
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with related proteins.
靶标信息
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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