Invitrogen

CtBP1 Polyclonal Antibody

查看其他23个CtBP1抗体

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说明书
实验方案
问题与答案
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说明书
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CtBP1 Polyclonal Antibody

产品信息

PA5-95014

应用
建议稀释比
已发表文章

免疫印迹 (WB)

0.1-0.5 µg/mL
-

免疫组化（石蜡） (IHC (P))

0.5-1 µg/mL
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence at the C-terminus of human CtBP1 (425-440aa QTVKPEADRDHASDQL).
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Affinity chromatography

保存液

PBS with 5mg BSA

内含物

0.05mg sodium azide, 0.05mg thimerosal

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2806820

产品详细信息

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: Rat Brain Tissue, Rat Testis Tissue, Rat Ovary Tissue, U87 Cell, SW620 Cell, HT1080 Cell, COLO32 Cell. IHC: Rat Brain Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

靶标信息

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 50 kDa BFA-dependent ADP-ribosylation substrate; 50-kDa BFA-induced ADP-ribosylated substrate; BARS-50; brefeldin A-ADP-riboslyated substrate; brefeldin A-ribosylated substrate; C-terminal-binding protein 1; C-terminal-binding protein 3; C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate; CtBP1; CtBP3; MGC104684

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基因别名: 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS; BARS-50; CTBP; CTBP1; CtBP1-L; CtBP1-S; Ctbp3; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E

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UniProt ID: (Human) Q13363, (Rat) Q9Z2F5, (Mouse) O88712

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Entrez Gene ID: (Human) 1487, (Rat) 29382, (Mouse) 13016

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功能
RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor protein domain specific binding protein homodimerization activity NAD binding repressing transcription factor binding transcription corepressor activity transferase activity, transferring acyl groups C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity gluconate dehydrogenase activity steroid dehydrogenase activity oxidoreductase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity transcription cofactor
参与通路
negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated protein phosphorylation negative regulation of cell proliferation viral genome replication positive regulation of histone deacetylation negative regulation of histone acetylation negative regulation of transcription, DNA-templated white fat cell differentiation regulation of cell cycle oxidation-reduction process negative regulation of histone H4 acetylation negative regulation of transcription from RNA polymerase II promoter by histone modification membrane fusion regulation of transcription, DNA-templated transcription from RNA polymerase II promoter metabolic process cell differentiation
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