This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Immunogen sequence: SEPFSFAQGP LKDAPNLICT PHTAWYSEQA SLEMREAAAT EIRRAITGRI PESLRNCVNK EFFVTSAPWS VIDQQAIHPE LNGATYRYPP GIVGVAPGGL PAAMEGIIPG GIPVTHNLPT VAHPSQAPSP NQPTKHGDNR EHPNEQ; Positive Samples: U-251MG, HeLa, BxPC3, Mouse brain, Rat brain; Cellular Location: Cell junction, Nucleus, synapse
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21. 3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
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蛋白别名: C-terminal-binding protein 2; CtBP2; gene trap ROSA b-geo 6; ribeye; RP11-59C5.2
基因别名: AA407280; CTBP2; D7Ertd45e; Gtrgeo6; Ribeye
分子生物学功能: transcription cofactor