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产品信息
PA5-50215
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to residues near the C terminal of human cullin 7 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.4 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635668 |
产品详细信息
The antibody detects endogenous levels of total Cullin 7 protein.
靶标信息
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CUL-7; Cullin-7
基因别名: 3M1; CUL7; dJ20C7.5; KIAA0076
UniProt ID: (Human) Q14999
Entrez Gene ID: (Human) 9820
microtubule cytoskeleton organization
mitotic cytokinesis
vasculogenesis
epithelial to mesenchymal transition
placenta development
proteolysis
ubiquitin-dependent protein catabolic process
Golgi organization
regulation of mitotic nuclear division
viral process
protein ubiquitination
IRE1-mediated unfolded protein response
positive regulation of dendrite morphogenesis
