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Proteintech
Cyclin G Polyclonal Antibody
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产品信息
10897-1-AP
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Cyclin G Fusion Protein Ag1157 (1-295 aa encoded by BC007093)
偶联物
形式
Liquid
浓度
0.13 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MIEVLTTTD SQKLLHQLNA LLEQESRCQP KVCGLRLIES AHDNGLRMTA RLRDFEVKDL LSLTQFFGFD TETFSLAVNL LDRFLSKMKV QPKHLGCVGL SCFYLAVKSI EEERNVPLAT DLIRISQYRF TVSDLMRMEK IVLEKVCWKV KATTAFQFLQ LYYSLLQENL PLERRNSINF ERLEAQLKAC HCRIIFSKAK PSVLALSIIA LEIQAQKCVE LTEGIECLQK HSKINGRDLT FWQELVSKCL TEYSSNECSK PNVQKLKWIV SGRTARQLKH SYYRITHLPT IPEMVP (1-295 aa encoded by B C007093)
靶标信息
Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
