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Invitrogen
Cyclophilin 40 Polyclonal Antibody
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Cyclophilin 40 Antibody (PA3-023) in ICC/IF
Immunofluorescence analysis of Cyclophilin 40 was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.01% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Cyclophilin 40 Polyclonal Antibody (Product # PA3-023) at 1:100 dilution in 0.1% BSA, incubated at 4 degree... View More
产品信息
PA3-023
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Amphibian,
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Full length, recombinant human CyP-40 expressed in E. coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
PBS, whole serum
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA3-023 detects cyclophilin 40 (CyP-40) from human, mouse and rat tissues and cells.
PA3-023 has been successfully used in Western blot and gel shift procedures. By Western blot, this antibody detects a 40 kDa protein representing CyP-40 from rat brain extract.
The PA3-023 immunogen is recombinant human CyP-40 expressed in E. coli.
靶标信息
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; Cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; PPIase; PPIase D; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147
基因别名: 4930564J03Rik; CYP-40; CYP40; CYPD; PPID; Ppidl; Ppif
UniProt ID: (Human) Q08752, (Mouse) Q9CR16, (Rat) Q6DGG0
Entrez Gene ID: (Human) 5481, (Mouse) 67738, (Rat) 361967
negative regulation of transcription from RNA polymerase II promoter
protein peptidyl-prolyl isomerization
protein folding
protein complex assembly
apoptotic process
protein transport
viral release from host cell
lipid particle organization
positive regulation of apoptotic process
positive regulation of viral genome replication
positive regulation of protein secretion
chaperone-mediated protein folding
cellular response to UV-A
transport
regulation of apoptotic process
response to oxidative stress
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
