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Invitrogen
Cytokeratin 14 Polyclonal Antibody
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产品信息
PA5-32460
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from C-terminus of human Keratin 14
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.235 mg/mL
规格
117.5 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Staining of formalin-fixed tissues requires digesting tissue sections with Pepsin for 10 min at 37°C, followed by incubation with primary antibody for 10 min at room temperature. A suggested positive control is skin or squamous cell carcinoma.
靶标信息
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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