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Invitrogen
Cytokeratin 5 Monoclonal Antibody (RCK103)
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产品信息
MA1-06312
应用
建议稀释比
已发表文章
产品规格
种属反应
Avian,
Dog,
Chicken,
Guinea pig,
Hamster,
Human,
Pig,
Rabbit,
Rat,
Zebrafish
已发表种属
C. elegans,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
RCK103
抗原
Mix of cell preparations containing human cytokeratins.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
purified
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-06312 detects basal cell cytokeratin in human, quail, chicken, rat, rabbit, hamster, canine, and guinea pig samples.
MA1-06312 has sucessfully been used in Western blotting, flow cytometry, immunocytochemistry, and immunohistochemistry. By Western blotting, it detects a ~300 kDa protein representing basal cell cytokeratin.
The MA1-06312 immunogen is a mix of cell preparations containing human cytokeratins.
靶标信息
Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 58 kDa cytokeratin; alpha keratin; CK-5; Cytokeratin-5; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; Keratin, type II cytoskeletal 5; Keratin-5; krt5; type II alpha-keratin IIA; type II cytokeratin; Type-II keratin Kb5
基因别名: CK5; ckii; DDD; DDD1; EBS2; K5; Krt2-5; KRT5; KRT5A; Sak57; wu:fb02h09; wu:fj02d02; wu:fk78b12; zfCKII
UniProt ID: (Human) P13647, (Rat) Q6P6Q2
