Invitrogen

DAB2IP Polyclonal Antibody

1 篇参考文献

查看其他8个DAB2IP抗体

问题与答案

问题与答案

问题与答案

Additional Information:

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抗体检测数据 (1)

DAB2IP Antibody in Western Blot (WB)

DAB2IP Antibody in Western Blot (WB)

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DAB2IP Antibody (48-7300) in WB

Western blot analysis of lysates prepared from DU145 human prostate carcinoma cells (lane A), SK-N-MC human neuroepithelioma cells (lane B) and B49 rat neural cells (lane C) using rabbit anti-DAB2IP antibody (Product # 48-7300).

DAB2IP Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

DAB2IP Antibody in Western Blot (WB) — Western blot analysis of lysates prepared from DU145 human prostate carcinoma cells (lane A), SK-N-MC human neuroepithelioma cells (lane B) and B49 rat neural cells (lane C) using rabbit anti-DAB2IP antibody (Product # 48-7300).

Immunogen image

DAB2IP Polyclonal Antibody

Immunogen Image DAB2IP Polyclonal Antibody

产品信息

48-7300

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

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产品规格

种属反应

Human, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide derived from the C-terminal region of the human DAB2IP protein

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

100 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.1% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: AIP-1; ASK-interacting protein 1; DAB2 interaction protein; DAB2-interacting protein; DIP1/2; disabled homolog 2 interacting protein; Disabled homolog 2-interacting protein; DOC-2/DAB-2 interactive protein; DOC-2/DAB2 interactive protein; DOC2/DAB2 interactive protein

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基因别名: AF9Q34; AIP-1; AIP1; DAB2IP; DIP1/2; KIAA1743

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UniProt ID: (Rat) Q6P730

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Entrez Gene ID: (Rat) 192126

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GTPase activator activity death receptor binding protein binding SH3 domain binding kinase binding protein kinase binding mitogen-activated protein kinase kinase binding mitogen-activated protein kinase kinase kinase binding phosphatidylinositol-3-phosphate binding protein complex binding signaling adaptor activity Toll-like receptor 4 binding phosphatidylinositol 3-kinase regulatory subunit binding identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 2 binding phosphatidylinositol 3-kinase binding protein N-terminus binding protein phosphatase 2A binding phosphatidylinositol-4-phosphate binding 14-3-3 protein binding GTPase-activating protein

negative regulation of transcription from RNA polymerase II promoter activation of MAPKKK activity angiogenesis negative regulation of protein phosphorylation apoptotic process response to unfolded protein I-kappaB phosphorylation activation of JUN kinase activity negative regulation of cell proliferation extrinsic apoptotic signaling pathway via death domain receptors negative regulation of endothelial cell migration negative regulation of epithelial cell migration negative regulation of epithelial to mesenchymal transition positive regulation of neuron projection development negative regulation of phosphatidylinositol 3-kinase signaling negative regulation of angiogenesis cell motility involved in cerebral cortex radial glia guided migration layer formation in cerebral cortex negative regulation of cell growth negative regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of NF-kappaB transcription factor activity negative regulation of toll-like receptor 4 signaling pathway negative regulation of GTPase activity tube formation negative regulation of catenin import into nucleus cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor receptor-2 signaling pathway reelin-mediated signaling pathway negative regulation of epidermal growth factor receptor signaling pathway positive regulation of apoptotic process regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling regulation of protein complex assembly negative regulation of MAP kinase activity positive regulation of MAPK cascade regulation of protein heterodimerization activity positive regulation of JUN kinase activity negative regulation of phosphatidylinositol 3-kinase activity cellular protein catabolic process positive regulation of protein catabolic process negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade negative regulation of Ras protein signal transduction negative regulation of fibroblast proliferation neuron projection morphogenesis positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress negative regulation of G0 to G1 transition negative regulation of ERK1 and ERK2 cascade positive regulation of cell cycle arrest cellular response to lipopolysaccharide cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus negative regulation of protein serine/threonine kinase activity positive regulation of protein serine/threonine kinase activity negative regulation of canonical Wnt signaling pathway positive regulation of synapse maturation positive regulation of dendrite development regulation of p38MAPK cascade negative regulation of vascular endothelial growth factor signaling pathway positive regulation of proteasomal protein catabolic process negative regulation of cyclin catabolic process positive regulation of neuron migration positive regulation of apoptotic signaling pathway