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Proteintech
DAP5 Polyclonal Antibody
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产品信息
17728-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DAP5 Fusion Protein Ag12125 (563-907 aa encoded by BC043149)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EAVNGVREM RAPKHFLPEM LSKVIILSLD RSDEDKEKAS SLISLLKQEG IATSDNFMQA FLNVLDQCPK LEVDIPLVKS YLAQFAARAI ISELVSISEL AQPLESGTHF PLFLLCLQQL AKLQDREWLT ELFQQSKVNM QKMLPEIDQN KDRMLEILEG KGLSFLFPLL KLEKELLKQI KLDPSPQTIY KWIKDNISPK LHVDKGFVNI LMTSFLQYIS SEVNPPSDET DSSSAPSKEQ LEQEKQLLLS FKPVMQKFLH DHVDLQVSAL YALQVHCYNS NFPKGMLLRF FVHFYDMEII EEEAFLAWKE DITQEFPGKG KALFQVNQWL TWLETAEEEE SEEEAD (563-907 aa encoded by BC043149)
靶标信息
CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: aging-associated protein 1; DAP-5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; Novel APOBEC-1 target 1; p97; Translation repressor NAT1
基因别名: AA589388; AAG1; DAP-5; DAP5; E130105L11Rik; EIF4G2; NAT1; Natm1; OK/SW-cl.75; P97
UniProt ID: (Human) P78344, (Mouse) Q62448
Entrez Gene ID: (Human) 1982, (Mouse) 13690
