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产品信息
PA5-37959
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-ESHNRFSATEVTNK, from the internal region of CCAR2 (aa842-855)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2554563
产品详细信息
This antibody is predicted to react with mouse, rat, dog, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
靶标信息
DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBC-1; DBC.1; DBCCR1; DBIRD complex subunit KIAA1967; deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; NET35; p30 DBC; p30 DBC protein
基因别名: 2610301G19Rik; CCAR2; DBC-1; DBC1; KIAA1967; mKIAA1967; NET35; p30 DBC; p30DBC
UniProt ID: (Human) Q8N163, (Mouse) Q8VDP4
Entrez Gene ID: (Human) 57805, (Mouse) 219158
transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
cell cycle
RNA splicing
response to UV
Wnt signaling pathway
negative regulation of cell growth
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of DNA-templated transcription, elongation
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of catalytic activity
mitochondrial fragmentation involved in apoptotic process
negative regulation of transcription, DNA-templated
rhythmic process
positive regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
regulation of cellular response to heat
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA damage checkpoint
regulation of transcription, DNA-templated
apoptotic process
