Search
Invitrogen
DCLK1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 5
DCLK1 Antibody (PA5-78281) in WB
Western blot was performed using Anti-DCLK1 Polyclonal Antibody (Product # PA5-78281) and a 80kDa band corresponding to DCLK1 was observed in IMR-32, Mouse Brain and Rat Brain, but not in BeWo, Mouse Kidney and Rat Kidney which are reported to be negative for DCLK1 expression. Whole cell lysates (30ug lysate) of IMR-32 (Lane 1), BeWo (Lane 2), tissue lysates (30ug lysate) of Mouse Brain (Lane 3), Mouse Kidney (Lane 4), Rat Brain (Lane 5) and Rat Kidney (Lane 6) and were electrophoresed using NuPAGE® 10 % Bis-Tris gel (Product # NP0302BOX).... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78281
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human DCLK1. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.77 mg/mL
规格
177 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse hippocampus, mouse brain, rat brain
Predicted Reactivity: Chicken (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CLICK-I beta; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin-like and CAM kinase-like 1; KIAA0369; RP11-113P14.1; similar to doublecortin and rat CPG16 kinase; unnamed protein product
基因别名: 1700113D08Rik; 2810480F11Rik; Ania4; CL1; Click-I; CLICK1; Cpg16; DCAMKL1; DCDC3A; Dcl; DCLK; mKIAA0369
UniProt ID: (Human) O15075, (Rat) O08875, (Mouse) Q9JLM8
Entrez Gene ID: (Human) 9201, (Rat) 83825, (Mouse) 13175
neuron migration
protein phosphorylation
axonogenesis
brain development
response to virus
peptidyl-serine phosphorylation
central nervous system projection neuron axonogenesis
forebrain development
axon extension
dendrite morphogenesis
regulation of postsynapse assembly
negative regulation of protein localization to nucleus
nervous system development
central nervous system development
endosomal transport
intracellular signal transduction
central nervous system neuron development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
