应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.1-0.5 µg/mL | - |
免疫组化(石蜡) (IHC (P)) |
0.5-1 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
0.1-0.5 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
E.coli-derived human DDR2 recombinant protein (Position: T801-E855). |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
500 µg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS with 4mg trehalose |
内含物 |
0.05mg sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2807353 |
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD167 antigen-like family member B; CD167b; CD167b antigen; CD_antigen: CD167b; cell migration-inducing protein 20; Discoidin domain receptor 2; discoidin domain receptor family, member 2; Discoidin domain-containing receptor 2; Discoidin domain-containing receptor tyrosine kinase 2; hydroxyaryl-protein; hydroxyaryl-protein kinase; migration-inducing gene 16 protein; neurotrophic tyrosine kinase receptor related 3; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; RP11-572K18.1; tyrosine-protein kinase TYRO 10; Tyrosine-protein kinase TYRO10; tyrosylprotein kinase
基因别名: AW495251; DDR2; MIG20a; NTRKR3; TKT; TYRO10
UniProt ID: (Human) Q16832, (Mouse) Q62371
Entrez Gene ID: (Human) 4921, (Mouse) 18214, (Rat) 685781
分子生物学功能:
transmembrane signal receptor