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Proteintech
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Immunogen sequence: TRELASQIH RELIKISEGT GFRIHMIHKA AVAAKKFGPK SSKKFDILVT TPNRLIYLLK QDPPGIDLAS VEWLVVDESD KLFEDGKTGF RDQLASIFLA CTSHKVRRAM FSATFAYDVE QWCKLNLDNV ISVSIGARNS AVETVEQELL FVGSETGKLL AVRELVKKGF NPPVLVFVQS IERAKELFHE LIYEGINVDV IHAERTQQQR DNTVHSFRAG KIWVLICTAL LARGIDFKGV NLVINYDFPT SSVEYIHRIG RTGRAGNKGK AITFFTEDDK PLLRSVANVI QQAGCPVPEY IKGFQKLLSK QKKKMIKKPL ERESISTTPK CFLEKAKDKQ KKVTGQNSKK KVALEDKS (243-599 aa encoded by BC041785)
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent RNA helicase ROK1-like; ATP-dependent, RNA helicase; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box protein 52; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 52; Probable ATP-dependent RNA helicase DDX52; rROK1L
基因别名: 2700029C06Rik; DDX52; HUSSY-19; HUSSY19; ROK1
UniProt ID: (Human) Q9Y2R4, (Mouse) Q8K301, (Rat) Q99PT0
Entrez Gene ID: (Human) 11056, (Mouse) 78394, (Rat) 85432