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Proteintech
DEDD Polyclonal Antibody
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产品信息
10816-1-AP
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DEDD Fusion Protein Ag1195 (1-318 aa encoded by BC013910)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAGLKRRAS QVWPEEHGEQ EHGLYSLHRM FDIVGTHLTH RDVRVLSFLF VDVIDDHERG LIRNGRDFLL ALERQGRCDE SNFRQVLQLL RIITRHDLLP YVTLKRRRAV CPDLVDKYLE ETSIRYVTPR ALSDPEPRPP QPSKTVPPHY PVVCCPTSGP QMCSKRPARG RATLGSQRKR RKSVTPDPKE KQTCDIRLRV RAEYCQHETA LQGNVFSNKQ DPLERQFERF NQANTILKSR DLGSIICDIK FSELTYLDAF WRDYINGSLL EALKGVFITD SLKQAVGHEA IKLLVNVDEE DYELGRQKLL RNLMLQALP (1-318 aa encoded by BC013910 )
靶标信息
DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDPro1; FLDED-1
基因别名: CASP8IP1; DEDD; DEDD1; DEDPRO1; DEFT; FLDED1; KE05
UniProt ID: (Human) O75618
Entrez Gene ID: (Human) 9191
transcription, DNA-templated
spermatogenesis
extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of protein catabolic process
regulation of apoptotic process
decidualization
negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
