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Invitrogen
DGKB Polyclonal Antibody
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DGKB Antibody (PA5-109630) in WB
Western blot analysis of DGKB in extracts of various cell lines. Samples were incubated with DGKB Polyclonal antibody (Product # PA5-109630) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-109630
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 544-773 of human DGKB (NP_663733.1).
偶联物
形式
Liquid
浓度
2.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LMKILKDIEN STEIMLDRWK FEVIPNDKDE KGDPVPYSII NNYFSIGVDA SIAHRFHIMR EKHPEKFNSR MKNKFWYFEF GTSETFSATC KKLHESVEIE CDGVQIDLIN ISLEGIAILN IPSMHGGSNL WGESKKRRSH RRIEKKGSDK RTTVTDAKEL KFASQDLSDQ LLEVVGLEGA MEMGQIYTGL KSAGRRLAQC SCVVIRTSKS LPMQIDGEPW MQTPCTVSTE
靶标信息
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 90 kDa diacylglycerol kinase; DAG kinase beta; DGK-beta; Diacylglycerol kinase 90kDa; Diacylglycerol kinase beta; diacylglycerol kinase beta, 90kDa; Diglyceride kinase beta
基因别名: 6430574F24; 90kda; C630029D13Rik; Dagk; DAGK2; DGK; DGK-beta; Dgkb; Kiaa0718; mKIAA0718
UniProt ID: (Rat) P49621, (Mouse) Q6NS52
Entrez Gene ID: (Rat) 54248, (Mouse) 217480
