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Product Details
MA5-21835
产品规格
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G5
Immunogen
DHH (NP_066382, 210 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
形式
Liquid
浓度
0.2-1.0 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2610277
Product Specific Information
Peptide Sequence: SGERKGLREL HRGDWVLAAD ASGRVVPTPV LLFLDRDLQR RASFVAVETE WPPRKLLLTP WHLVFAARGP APAPGDFAPV FARRLRAGDS VLAPGGDALR P*
Target Information
This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Desert hedgehog protein; Desert hedgehog protein N-product; DHH; DHH-N; HHG-3
Gene Aliases: DHH; GDXYM; HHG-3; SRXY7
UniProt ID: (Human) O43323
Entrez Gene ID: (Human) 50846
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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