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Invitrogen
DHODH Polyclonal Antibody
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DHODH Antibody (PA5-79153) in IHC (P)
Immunohistochemistry analysis of DHODH on paraffin-embedded human lung cancer tissue. Sample was incubated with DHODH polyclonal antibody (Product# PA5-79153) with a dilution of 1 µg/mL, and developed by Streptavidin-Biotin-Complex (SABC) with DAB chromogen method.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79153
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human DHODH (132-173aa RVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTE D).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human A431 whole cell, human HepG2 whole cell, human MCF-7 whole cell, rat testis tissue, rat liver tissue, mouse testis tissue, mouse liver tissue. IHC: mouse intestine tissue, rat intestine tissue, human lung cancer tissue.
靶标信息
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; dihydroorotate dehydrogenase, mitochondrial; Dihydroorotate oxidase
基因别名: 2810417D19Rik; AI834883; DHODH
UniProt ID: (Rat) Q63707, (Mouse) O35435
Entrez Gene ID: (Rat) 65156, (Mouse) 56749
'de novo' pyrimidine nucleobase biosynthetic process
female pregnancy
lactation
response to organic cyclic compound
response to caffeine
response to drug
response to starvation
positive regulation of apoptotic process
'de novo' UMP biosynthetic process
oxidation-reduction process
regulation of mitochondrial fission
pyrimidine nucleotide biosynthetic process
UMP biosynthetic process
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