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Invitrogen
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PA1-25000 detects DIAPH1 from human samples. PA1-25000 is expected to cross react with mouse due to sequence homology.
PA1-25000 has been successfully used in Western blot procedures.
The PA1-25000 immunogen is a synthetic peptide corresponding to a portion of the human diaphanous homolog 1 encoded within exon 27.
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。