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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ELCDRDVRAC SSAPCANNGT CVSLDDGLYE CSCAPGYSGK DCQKKDGPCV INGSPCQHGG TCVDDEGRAS HASCLCPPGF SGNFCEIVAN SCTPNPCEND GVCTDIGGDF RCRCPAGFID KTCSRPVTNC ASSPCQNGGT CLQHTQVSYE CLCKPEFTGL TCVKKRALSP QQVTRLPSGY GLAYRLTPGV HELPVQQPEH RILKVSMKEL NKKTPLLTEG QAICFTILGV LTSLVVLGTV GIVFLNKCET WVSNLRYNHM LRKKKNLLLQ YNSGEDLAVN IIFPEKIDMT TFSKEAGDEE I; Positive Samples: HepG2, Mouse brain, Mouse heart; Cellular Location: Membrane, Single-pass type I membrane protein
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adipocyte differentiation inhibitor protein; DLK-1; fetal antigen 1; Preadipocyte factor 1; PREF; Pref-1; Protein delta homolog 1; stromal cell derived protein 1
基因别名: AW742678; Dlk; DLK-1; Dlk1; DlkI; FA1; Ly107; Peg9; pG2; pref-1; Pref1; Scp-1; SCP1; ZOG
UniProt ID: (Mouse) Q09163
Entrez Gene ID: (Mouse) 13386