Invitrogen

DLL1 Polyclonal Antibody

1 Published Figure
1 Reference
View all (18) DLL1 antibodies
Datasheet
Protocols
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Datasheet
Protocols
Tech Support

Product Details

PA5-42902

Applications
Tested Dilution
Publications

免疫印迹 (WB)

0.2-1 µg/mL
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免疫组化 (IHC)

5 µg/mL
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产品规格

Species Reactivity

Human, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

分类

Polyclonal

类型

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human DLL1
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Conjugate

Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2610508

Product Specific Information

Peptide sequence: GSRCALALAV LSALLCQVWS SGVFELKLQE FVNKKGLLGN RNCCRGGAGP

Sequence homology: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Target Information

Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Bioinformatics

Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

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Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

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UniProt ID: (Human) O00548, (Rat) P97677

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Entrez Gene ID: (Human) 28514, (Rat) 84010

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Function(s)
cell fate determination somitogenesis somite specification heart looping Notch signaling pathway cell-cell signaling determination of left/right symmetry compartment pattern specification nervous system development auditory receptor cell fate commitment negative regulation of interleukin-10 production negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter inner ear development regulation of neurogenesis left/right axis specification proximal tubule development loop of Henle development neuronal stem cell population maintenance marginal zone B cell differentiation type B pancreatic cell development Notch receptor processing regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis cell differentiation regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation positive regulation of endocytosis lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment nephron development clathrin-mediated endocytosis endothelial tip cell fate specification skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis
Process(es)
Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding
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