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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • DLL1 Antibodies

          Invitrogen

          DLL1 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (18) DLL1 antibodies
          Datasheet
          Protocols
          Tech Support

          Cite DLL1 Polyclonal Antibody

          Datasheet
          Protocols
          Tech Support
          • Antibody Testing Data (3)
          • Published Figures (1)
          DLL1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          DLL1 Antibody (PA5-42902) in WB

          Western blot was performed using Anti-DLL1 Polyclonal Antibody (Product # PA5-42902) and ~78kDa band corresponding to DLL1 was observed across all the cell lines and tissues tested. Membrane extracts (30 µg lysate) of IMR-32 (Lane 1), SH-SY5Y (Lane 2), PANC-1 (Lane 3), MCF7 (Lane 4), THP-1 (Lane 5), Mouse Spleen (Lane 6), Rat Spleen (Lane 7), Rat Heart (Lane 8) and Mouse Heart (Lane 9) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Product Details

          PA5-42902

          Applications
          Tested Dilution
          Publications

          免疫印迹 (WB)

          0.2-1 µg/mL
          查看1篇已发表文章 1篇已发表文章

          免疫组化 (IHC)

          5 µg/mL
          -
          产品规格

          Species Reactivity

          Human, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          Immunogen

          Synthetic peptide directed towards the N-terminal of human DLL1
          View immunogen

          Conjugate

          Unconjugated

          形式

          Liquid

          浓度

          0.5 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS with 2% sucrose

          内含物

          0.09% sodium azide

          保存条件

          -20° C, Avoid Freeze/Thaw Cycles

          RRID

          AB_2610508

          Product Specific Information

          Peptide sequence: GSRCALALAV LSALLCQVWS SGVFELKLQE FVNKKGLLGN RNCCRGGAGP

          Sequence homology: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

          Target Information

          Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          Bioinformatics

          Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

          View more View less

          Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

          View more View less

          UniProt ID: (Human) O00548, (Rat) P97677

          View more View less

          Entrez Gene ID: (Human) 28514, (Rat) 84010

          View more View less

          Function(s)
          cell fate determination somitogenesis somite specification heart looping Notch signaling pathway cell-cell signaling determination of left/right symmetry compartment pattern specification nervous system development auditory receptor cell fate commitment negative regulation of interleukin-10 production negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter inner ear development regulation of neurogenesis left/right axis specification proximal tubule development loop of Henle development neuronal stem cell population maintenance marginal zone B cell differentiation type B pancreatic cell development Notch receptor processing regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis cell differentiation regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation positive regulation of endocytosis lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment nephron development clathrin-mediated endocytosis endothelial tip cell fate specification skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis
          Process(es)
          Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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