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Proteintech
DNA2 Polyclonal Antibody
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产品信息
21599-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DNA2 Fusion Protein Ag16206 (1-350 aa encoded by BC111740)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is specific to DNA2.
Immunogen sequence: MEQLNELEL LMEKSFWEEA ELPAELFQKK VVASFPRTVL STGMDNRYLV LAVNTVQNKE GNCEKRLVIT ASQSLENKEL CILRNDWCSV PVEPGDIIHL EGDCTSDTWI IDKDFGYLIL YPDMLISGTS IASSIRCMRR AVLSETFRSS DPATRQMLIG TVLHEVFQKA INNSFAPEKL QELAFQTIQE IRHLKEMYRL NLSQDEIKQE VEDYLPSFCK WAGDFMHKNT STDFPQMQLS LPSDNSKDNS TCNIEVVKPM DIEESIWSPR FGLKGKIDVT VGVKIHRGYK TKYKIMPLEL KTGKESNSIE HRSQVVLYTL LSQERRADPE AGLLLYLKTG QMYPVPANHL D (1-350 aa encoded by BC111740)
靶标信息
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA2-like helicase; hDNA2
基因别名: DNA2; DNA2L; E130315B21Rik; hDNA2; KIAA0083
UniProt ID: (Human) P51530, (Mouse) Q6ZQJ5
Entrez Gene ID: (Human) 1763, (Mouse) 327762
DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleotide binding
catalytic activity
endonuclease activity
hydrolase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
iron-sulfur cluster binding
DNA replication checkpoint
DNA double-strand break processing
DNA replication
mitochondrial DNA replication
DNA repair
base-excision repair
cellular response to DNA damage stimulus
metabolic process
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
telomere maintenance via recombination
telomere maintenance
DNA synthesis involved in DNA repair
strand displacement
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication
