FIGURE: 1 / 2
Peptide Sequence: MEANMPKRKE PGRSLRIKVI SMGNAEVGKS CIIKRYCEKR FVSKYLATIG IDYGVTKVHV RDREIKVNIF DMAGHPFFYE VRNEFYKDTQ GVILVYDVGQ KDSFDALDAW LAEMKQELGP HGNMENIIFV VCANKIDCTK HRCVDESEGR LWAESKGFLY FETSAQTGEG INEMFQTFYI SIVDLCENGG KRPTTNSSAS FTKEQADAIR RIRNSKDSWD MLGVKPGASR DEVNKAYRKL AVLLHPDKCV APGSEDAFKA VVNARTALLK NIK
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
Protein Aliases: APAH1; DnaJ (Hsp40) homolog, subfamily C, member 27; DnaJ homolog subfamily C member 27; Rab and DnaJ domain-containing protein; Ras-associated protein Rap1
Gene Aliases: DNAJC27; RABJS; RBJ
UniProt ID: (Human) Q9NZQ0
Entrez Gene ID: (Human) 51277