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Proteintech
DNMT2 Polyclonal Antibody
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产品信息
19221-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DNMT2 Fusion Protein Ag5571 (1-391 aa encoded by BC047733)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEPLRVLEL YSGVGGMHHA LRESCIPAQV VAAIDVNTVA NEVYKYNFPH TQLLAKTIEG ITLEEFDRLS FDMILMSPPC QPFTRIGRQG DMTDSRTNSF LYILDILPRL QKLPKYILLE NVKGFEVSST RDLLIQTIEN CGFQYQEFLL SPTSLGIPNS RLRYFLIAKL QSEPLPFQAP GQVLMEFPKI ESVHPQKYAM DVENKIQEKN VEPNISFDGS IQCSGKDAIL FKLETAEEIH RKNQQDSDLS VKMLKDFLED DTDVNQYLLP PKSLLRYALL LDIVQPTCRR SVCFTKGYGS YIEGTGSVLQ TAEDVQVENI YKSLTNLSQE EQITKLLILK LRYFTPKEIA NLLGFPPEFG FPEKITVKQR YRLLGNSLNV HVVAKLIKIL YE (1-391 aa encoded by BC047733)
靶标信息
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met-2; PuMet; RP11-406H21.1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase
基因别名: DMNT2; DNMT2; Met2; MHSAIIP; PUMET; RNMT1; Rnmt2; TRDMT1
UniProt ID: (Human) O14717, (Mouse) O55055, (Rat) Q4G073
Entrez Gene ID: (Human) 1787, (Mouse) 13434, (Rat) 291324
