FIGURE: 1 / 1
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Protein Aliases: 180 kDa protein downstream of CRK; Dedicator of cytokinesis protein 1; dock 180; DOCK180; DOwnstream of CrK; RP11-82L9.1
Gene Aliases: ced5; DOCK1; DOCK180
UniProt ID: (Human) Q14185
Entrez Gene ID: (Human) 1793
Molecular Function: guanyl-nucleotide exchange factor