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Invitrogen
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The antibody detects endogenous levels of total DOK4 protein.
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Docking protein 4; Downstream of tyrosine kinase 4; Insulin receptor substrate 5; IRS-5
基因别名: DOK4; IRS-5; IRS5
UniProt ID: (Human) Q8TEW6, (Mouse) Q99KE3
Entrez Gene ID: (Human) 55715, (Mouse) 114255