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The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; MGC16926; Protein dok-5
基因别名: 2700055C10Rik; C20orf180; DOK5; IRS-6; IRS6
UniProt ID: (Human) Q9P104, (Mouse) Q91ZM9
Entrez Gene ID: (Human) 55816, (Mouse) 76829