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Invitrogen
DOT5 Polyclonal Antibody
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产品信息
PA5-144581
产品规格
种属反应
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant S. cerevisiae DOT5 protein (37-118aa)
偶联物
形式
Liquid
浓度
3.25 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Disrupter of telomere silencing protein 5; nTPx; Nuclear thiol peroxidase; Peroxiredoxin DOT5; Peroxiredoxin DOT5 DOT5 YIL010W; Prx; Thioredoxin peroxidase; Thioredoxin-dependent peroxiredoxin DOT5
基因别名: DOT5; YIL010W
UniProt ID: (Baker's yeast) P40553
Entrez Gene ID: (Baker's yeast) 854805
