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Invitrogen
DPP10 (extracellular) Polyclonal Antibody
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DPP10 (extracellular) Antibody (PA5-111885) in IHC (F)
Immunohistochemistry analysis of DPP10 in perfusion-fixed, frozen mouse cerebellum and hippocampus tissue sections using DPP10 (extracellular) Antibody (Product # PA5-111885) at a dilution of 1:1000, followed by goat anti-rabbit-AlexaFluor-488. A) DPP10 immunoreactivity (green) in mouse cerebellum is detected in the Purkinje cell layer (P) in Purkinje cells (arrows) and diffusely in the molecular layer (MOL... View More
产品信息
PA5-111885
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 356-370 of rat DPP10 (Extracellular, C-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: CSRKYEMTSD TWISK
Homology: Mouse - 14/15 amino acid residues identical; human - 12/15 amino acid residues identical.
靶标信息
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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