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Proteintech
DRG1 Polyclonal Antibody
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产品信息
13190-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DRG1 Fusion Protein Ag3866 (1-367 aa encoded by BC020803)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSSTLAKIA EIEAEMARTQ KNKATAHHLG LLKARLAKLR RELITPKGGG GGGPGEGFDV AKTGDARIGF VGFPSVGKST LLSNLAGVYS EAAAYEFTTL TTVPGVIRYK GAKIQLLDLP GIIEGAKDGK GRGRQVIAVA RTCNLILIVL DVLKPLGHKK IIENELEGFG IRLNSKPPNI GFKKKDKGGI NLTATCPQSE LDAETVKSIL AEYKIHNADV TLRSDATADD LIDVVEGNRV YIPCIYVLNK IDQISIEELD IIYKVPHCVP ISAHHRWNFD DLLEKIWDYL KLVRIYTKPK GQLPDYTSPV VLPYSRTTVE DFCMKIHKNL IKEFKYALVW GLSVKHNPQK VGKDHTLEDE DVIQIVKK (1-367 aa encoded by BC020803)
靶标信息
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155). Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions (PubMed:23711155). When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238). Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: developmentally regulated GTP-binding protein 1; Developmentally-regulated GTP-binding protein 1; DRG-1; NEDD-3; Neural precursor cell expressed developmentally down-regulated protein 3; neural precursor cell expressed, developmentally down-regulated 3; TRAFAC GTPase DRG1; Translation factor GTPase DRG1
基因别名: DRG1; NEDD3
UniProt ID: (Human) Q9Y295
Entrez Gene ID: (Human) 4733, (Rat) 305470
