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Immunogen sequence: SCTGTLVVHL DDYNDHAPQI DKEVTICQNN EDFAVLKPVD PDGPENGPPF QFFLDNSASK NWNIEEKDGK TAILRQRQNL DYNYYSVPIQ IKDRHGLVAT HMLTVRVCDC STPSECRMKD KSTR
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 70%.
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin family member 1; Desmocollin-1; Desmocollin1; Desmosomal glycoprotein 2/3; DG2/DG3
基因别名: CDHF1; DG2/DG3; DSC1
UniProt ID: (Human) Q08554
Entrez Gene ID: (Human) 1823
分子生物学功能:
cadherin