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Invitrogen
DSC1 Polyclonal Antibody
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DSC1 Antibody (PA5-87603) in WB
Western blot analysis of DSC1 in extracts of various cell lines. Samples were incubated with DSC1 Polyclonal antibody (Product # PA5-87603) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-87603
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 480-690 of human DSC1 (NP_0777391)
偶联物
形式
Liquid
浓度
2.29 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SQDGFPAGQE LLGYKALDPE ISSGEGLRYQ KLGDEDNWFE INQHTGDLRT LKVLDRESKF VKNNQYNISV VAVDAVGRSC TGTLVVHLDD YNDHAPQIDK EVTICQNNED FAVLKPVDPD GPENGPPFQF FLDNSASKNW NIEEKDGKTA ILRQRQNLDY NYYSVPIQIK DRHGLVATHM LTVRVCDCST PSECRMKDKS TRDVRPNVIL G; Positive Samples: Raji, Mouse liver, Rat liver; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome
靶标信息
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cadherin family member 1; Desmocollin-1; Desmocollin1; Desmosomal glycoprotein 2/3; DG2/DG3
基因别名: 1110020A10Rik; AI507491; CDHF1; DG2/DG3; DSC1; Dsc1a; Dsc1b
UniProt ID: (Human) Q08554, (Mouse) P55849
Entrez Gene ID: (Human) 1823, (Rat) 291759, (Mouse) 13505
