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Proteintech
DTNA Polyclonal Antibody
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产品信息
10741-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DTNA Fusion Protein Ag1075 (1-374 aa encoded by BC005300)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MIEDSGKRG NTMAERRQLF AEMRAQDLDR IRLSTYRTAC KLRFVQKKCN LHLVDIWNVI EALRENALNN LDPNTELNVS RLEAVLSTIF YQLNKRMPTT HQIHVEQSIS LLLNFLLAAF DPEGHGKISV FAVKMALATL CGGKIMDKLR YIFSMISDSS GVMVYGRYDQ FLREVLKLPT AVFEGPSFGY TEQSARSCFS QQKKVTLNGF LDTLMSDPPP QCLVWLPLLH RLANVENVFH PVECSYCHSE SMMGFRYRCQ QCHNYQLCQD CFWRGHAGGS HSNQHQMKEY TSWKSPAKKL TNALSKSLSC ASSREPLHPM FPDQPEKPLN LAHIVPPRPV TSMNDTLFSH SVPSSGSPFI TRSSDGAFGG CV (1-374 aa encoded by BC005300)
靶标信息
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-dystrobrevin; DTN-A; Dystrobrevin alpha; dystrobrevin alpha, pseudogene 1; dystrobrevin, alpha; Dystrophin-related protein 3
基因别名: 2210407P21Rik; a-DB-1; adbn; D18S892E; DRP3; DTN; DTN-A; DTNA; Dtna-ps1; Gm19389; LVNC1; RGD1561985
UniProt ID: (Human) Q9Y4J8, (Mouse) Q9D2N4
Entrez Gene ID: (Human) 1837, (Rat) 307548, (Mouse) 13527
