Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫组化 (IHC) |
1:200-1:500 | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human DYNC1I1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2640844 |
Immunogen sequence: LQSDSELGRR LHKLGVSKVT QVDFLPREVV SYSKETQTPL ATHQSEEDEE DEE
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; DH IC-1; Dynein intermediate chain 1, cytosolic; dynein, cytoplasmic 1, intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1
基因别名: DNCI1; DNCIC1; DYNC1I1
UniProt ID: (Human) O14576
Entrez Gene ID: (Human) 1780
分子生物学功能:
microtubule or microtubule-binding cytoskeletal protein