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Invitrogen
DYNC2LI1 Polyclonal Antibody
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DYNC2LI1 Antibody (PA5-120891) in WB
Western blot analysis of DYNC2LI1 in extracts of various cell lines. Samples were incubated with DYNC2LI1 Polyclonal antibody (Product # PA5-120891) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-120891
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: U-251MG, Jurkat, 293T, A-549, Mouse testis, Mouse eye, Mouse kidney, Rat testis. The target is usually found in the following locations: Cytoplasm, cilium axoneme, cytoskeleton.
Immunogen sequence: MPSETLWEIA KAEVEKRGIN GSEGDGAEIA EKFVFFIGSK NGGKTTIILR CLDRDEPPKP TLALEYTYGR RAKGHNTPKD IAHFWELGGG TSLLDLISIP ITGDTLRTFS LVLVLDLSKP NDLWPTMENL LQATKSHVDK VIMKLGKTNA KAVSEMRQKI WNNMPKDHPQ DHELIDPFPV PLVIIGSKYD VFQDFESEKR KVICKTLRFV AHYYGASLMF TSKSEALLLK IRGVINQLAF GIDKSKSICV DQNKPLFITA GLDSFGQIGS PPVPENDIGK LHAHSPMELW KKVYEKLFPP KSINTLKDIK DPARDPQYAE NEVDEMRIQK DLELEQYKRS SSKSWKQIEL DS
靶标信息
DYNC2LI1 (dynein, cytoplasmic 2, light intermediate chain 1), also known as LIC3, D2LIC or CGI-60, is a 351 amino acid cytoplasmic protein belonging to the dynein light intermediate chain family. DYNC2LI1 may function as a motor for intraflagellar retrograde transport and in cilia biogenesis. The cytoplasmic dynein complex 2 may be composed of a DYNC2H1 homodimer and a number of DYNC2LI1 light intermediate chains. DYNC2LI1 exists as five alternatively spliced isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytoplasmic dynein 2 light intermediate chain 1; Dynein 2 light intermediate chain; dynein, cytoplasmic 2, light intermediate chain 1; mD2LIC
基因别名: 4933404O11Rik; CGI-60; D2LIC; DYNC2LI1; LIC3; mD2LIC; RGD1310286
UniProt ID: (Human) Q8TCX1, (Mouse) Q8K0T2
Entrez Gene ID: (Human) 51626, (Mouse) 213575, (Rat) 298767
