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Invitrogen
Decapentaplegic Monoclonal Antibody (146609)
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产品信息
MA5-61008
产品规格
种属反应
Fruit fly
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
146609
抗原
E. coli-derived recombinant Drosophila Decapentaplegic/DPP, Asp457-Arg588 (Gln473His, Pro474Ala)
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Decapentaplegic (Dpp) is a gene in Drosophila melanogaster, encoding a protein that is a member of the Transforming Growth Factor-beta (TGF-beta) superfamily. Dpp plays a crucial role in various developmental processes, including embryogenesis, organogenesis, and the regulation of cell growth and differentiation. It functions primarily as a morphogen, a signaling molecule that forms a concentration gradient to provide positional information to cells, guiding their development and differentiation. Dpp is essential for the proper patterning of tissues and organs, such as the wings, legs, and gut in fruit flies. Mutations in the Dpp gene can lead to severe developmental abnormalities and defects in tissue patterning. The study of Dpp and its signaling pathways provides valuable insights into the mechanisms of morphogen-mediated development and has broader implications for understanding similar TGF-beta signaling pathways in other organisms, including humans.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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