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GenScript
Denosumab Monoclonal Antibody (9A10)
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Denosumab Antibody (A02102-40) in ELISA
Anti-Denosumab Antibody (9A10) (GenScript, A02102-40) blocks Denosumab binding with Human RANKL recombinant protein. Coating antigen: Denosumab 1 µg/mL. RANKL final concentration: 12.5 ng/mL. Anti-Denosumab antibody dilutions start from 30 μg/mL. IC50= 0.893 µg/mL.
产品信息
A02102-40
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
9A10
抗原
Denosumab
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Competitive ELISA recommended dilution: 5-30 µg/mL
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
靶标信息
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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