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Invitrogen
Diquat Recombinant Mouse Monoclonal Antibody (2B6)
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Diquat Antibody (MA566536) in SDS-PAGE
SDS-PAGE characterization of Diquat under reducing conditions. Lane M: Protein marker (kDa); Lane DQ: Purified Diquat Recombinant Monoclonal (Product # MA566536). Diquat showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-559.
产品信息
MA566536
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B6
抗原
Conjugate of DQ hapten and KLH.
偶联物
形式
Liquid
浓度
5.8 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Diquat is a bipyridine herbicide extensively used in agricultural and non-agricultural settings, known for its high toxicity and potential to cause neuronal disorders and liver damage. It induces oxidative stress and inflammation, leading to cell death and dopamine neuron loss. The molecular mechanisms of diquat toxicity involve mitochondrial dysfunction and oxidative stress, which have been studied using various models, including diquat-induced liver injury in mice and single-cell analysis. Protective agents like silymarin and baicalin have been researched for their ability to mitigate diquat-induced damage by reducing inflammation and oxidative stress. The adsorption and elimination of diquat using advanced materials like layer double hydroxide and hydrogel beads have also been explored to minimize environmental impact.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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