Proteintech

Dynamitin (1-401 AA) Monoclonal Antibody (2B9A5)

Name: Dynamitin (1-401 AA) Monoclonal Antibody (2B9A5)
Brand: Proteintech
SKU: 60257-1-IG

1 篇参考文献

查看其他14个Dynactin 2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)

Dynamitin (1-401 AA) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 3

Dynamitin (1-401 AA) Antibody (60257-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas slide using 60257-1-IG ( Dynamitin antibody at dilution of 1:50.

Dynamitin (1-401 AA) Antibody in Western Blot (WB)

Product Image Gallery

Immunogen image

Immunogen Image Dynamitin (1-401 AA) Monoclonal Antibody (2B9A5)

产品信息

60257-1-IG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG3

分类

Monoclonal

类型

Antibody

克隆号

2B9A5

抗原

Dynamitin (1-401 AA) Fusion Protein Ag1902 (1-401 aa encoded by BC014083)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

This antibody is against the N terminal 86aa of full length p50 dynamitin.

Immunogen sequence: MADPKYADL PGIARNEPDV YETSDLPEDD QAEFDAEELT STSVEHIIVN PNAAYDKFKD KRVGTKGLDF SDRIGKTKRT GYESGEYEML GEGLGVKETP QQKYQRLLHE VQELTTEVEK IKTTVKESAT EEKLTPVLLA KQLAALKQQL VASHLEKLLG PDAAINLTDP DGALAKRLLL QLEATKNSKG GSGGKTTGTP PDSSLVTYEL HSRPEQDKFS QAAKVAELEK RLTELETAVR CDQDAQNPLS AGLQGACLME TVELLQAKVS ALDLAVLDQV EARLQSVLGK VNEIAKHKAS VEDADTQSKV HQLYETIQRW SPIASTLPEL VQRLVTIKQL HEQAMQFGQL LTHLDTTQQM IANSLKDNTT LLTQVQTTMR ENLATVEGNF ASIDERMKKL GK (1-401 aa encoded by BC014083)

靶标信息

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: 50 kDa dynein-associated polypeptide; DCTN-50; dynactin 2 (p50); Dynactin complex 50 kDa subunit; Dynactin subunit 2; epididymis secretory protein Li 77; GMP23-48K; Growth cone membrane protein 23-48K; p50 dynamitin

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基因别名: 2310042E05Rik; C130077D06Rik; C87049; DCTN-50; DCTN2; DCTN50; DYNAMITIN; GMP23-48K; HEL-S-77; p50; RBP50

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UniProt ID: (Human) Q13561, (Mouse) Q99KJ8

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Entrez Gene ID: (Human) 10540, (Mouse) 69654

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功能

motor activity protein binding spectrin binding microtubule binding motor protein

参与通路

G2/M transition of mitotic cell cycle ER to Golgi vesicle-mediated transport microtubule-based process mitotic spindle organization mitotic nuclear division cell proliferation antigen processing and presentation of exogenous peptide antigen via MHC class II melanosome transport protein localization to centrosome