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Invitrogen
Dynorphin A Polyclonal Antibody
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产品信息
PA1-84557
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Dynorphin A: AA-Residues 1-17 (porcine)
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存条件
4°C or -20°C if preferred
运输条件
Wet ice
RRID
产品详细信息
This antibody binds to both dynorphin A 1-17 and 1-8 but not with other big dynorphin cleavage products such as dynorphin B, also known as rimorphin.
This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase. Overnight incubation with primary antibody is recommended.
The immunogen used to produce PA1-84557 is from Dynorphin A 1-17: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln (porcine).
Rabbit anti Human dynorphin A antibody recognizes the opioid peptide dynorphin A (Fischli et al. 1982), a cleavage product of big dynorphin, itself derived from the precursor pro-encephalin-B, also known as preprodynorphin.
靶标信息
The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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