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Proteintech
Dysbindin Polyclonal Antibody
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产品信息
11132-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Dysbindin Fusion Protein Ag1613 (1-351 aa encoded by BC011912)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody recognizes all of isoforms of dysbindin.
Immunogen sequence: MLETLRERL LSVQQDFTSG LKTLSDKSRE AKVKSKPRTV PFLPKYSAGL ELLSRYEDTW AALHRRAKDC ASAGELVDSE VVMLSAHWEK KKTSLVELQE QLQQLPALIA DLESMTANLT HLEASFEEVE NNLLHLEDLC GQCELERCKH MQSQQLENYK KNKRKELETF KAELDAEHAQ KVLEMEHTQQ MKLKERQKFF EEAFQQDMEQ YLSTGYLQIA ERREPIGSMS SMEVNVDMLE QMDLMDISDQ EALDVFLNSG GEENTVLSPA LGPESSTCQN EITLQVPNPS ELRAKPPSSS STCTDSATRD ISEGGESPVV QSDEEEVQVD TALATSHTDR EATPDGGEDS DS (1-351 aa encoded by BC011912)
靶标信息
Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: biogenesis of lysosomal organelles complex-1, subunit 8; Biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; distrobrevin binding protein 1; DKFZp564K192; DTBP1; Dysbindin; Dysbindin-1; Dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; Hermansky-Pudlak syndrome 7 protein homolog; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy
基因别名: 5430437B18Rik; AW048963; BLOC1S8; DBND; DTNBP1; dysbindin; HPS7; My031; SDY
UniProt ID: (Human) Q96EV8, (Mouse) Q91WZ8, (Rat) Q5M834
Entrez Gene ID: (Human) 84062, (Mouse) 94245, (Rat) 641528
positive regulation of neurotransmitter secretion
blood coagulation
anterograde axonal transport
positive regulation of gene expression
regulation of dopamine secretion
neuron projection development
actin cytoskeleton reorganization
melanosome organization
regulation of JUN kinase activity
anterograde synaptic vesicle transport
neuron projection morphogenesis
platelet dense granule organization
regulation of dopamine receptor signaling pathway
organelle organization
muscle organ development
response to stimulus
