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Invitrogen
Dystrophin Polyclonal Antibody
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产品信息
PA1-21011
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to C-terminal of human Dystrophin.
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-21011 detects Dystrophin in Human, Mouse and Rat samples.
PA1-21011 has been successfully used in Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) immunocytochemistry, immunofluorescence, and Western Blot procedures. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0 for 10 minutes followed by cooling at room temperature for 20 minutes. Positive control of skeletal muscle suggested. Molecular weight of 427 kDa is expected.
PA1-21011 immunogen corresponds to a synthetic peptide corresponding to C-terminal of human Dystrophin.
靶标信息
Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
